Multi-Disciplinary Organization Dedicated to Promoting Advances in
Neuro-Oncology Through Research and Education

WFNOS Magazine

The inaugural issue of the official publication of the World Federation of Neuro-Oncology Societies is ...

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Neuro-Oncology Review Course at SNO

November 16, 2016. Register in conjunction with the SNO Annual Meeting

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CNS Anticancer Drug Discovery and Development Conference

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EANO 2016

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18th Annual Brain Tumor Update and 7th Annual International Symposium on Long-Term Control of Metastases to the Brain and Spine

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2nd CNS Anticancer Drug Discovery/Development Conference

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2011 Neuro-Tumor Club Dinner Program


9840 International Drive
Orlando, Florida 32819

MONDAY, APRIL 04, 2011 6:30PM – 10:00PM

6:30-7:00 Buffet Dinner Service

7:00-7:05 Introductions and Acknowledgments
Waldemar Debinski
, Wake Forest University, and Hideho Okada, University of Pittsburgh

Session 1: Geno/Phenotyping and Personalized/Combinatorial Therapy
7:05-7:10 Overview: Michael D. Taylor, University of Toronto, Canada

7:10-7:15 1 Irene Vassallo, Chuv, Lausanne, France
The Wnt inhibitory Factor 1 has tumor suppressing functions in glioblastoma potentially by inducing cellular senescence

7:20-7:25 2 Lonneke A.M. Gravendeel, Erasmus MC, Rotterdam, the Netherlands
Tetraploid gliomas share molecular features with pilocytic astrocytomas

7:30-7:35 3 Marc Remke, German Cancer Research Center, Heidelberg, Germany
Integrated genomic approach indicates three major molecular variants in adult medulloblastoma

7:40-7:45 4, Huriye Cin, German Cancer Research Center, Heidleberg, Germany
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises and alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

Session 2: Angiogenesis and Tumor Microenvironment
7:50-7:55 Overview: Linda J. Metheny-Barlow, Wake Forest University, Winston-Salem, NC

7:55-8:00 5 Yvan Chanthery, UCSF, San Francisco, CA
Paracrine signaling through Mycn enhances tumor-vascular interactions in neuroblastoma

8:05-8:10 6 Daniel J. Brat, Emory University, Atlanta, GA
Integrated analysis of necrosis, angiogenesis, and gene expression in glioblastoma

8:15-8:20 7 Maria Castro, Gene Therapeutics Research Institute, UCLA, Los Angeles, CA
Glioma-derived factors induce the expansion of myeloid-derived suppressor cells (MDSCs) that facilitate immune suppression and tumor progression

Session 3: New Tools and Translational Science
8:25-8:30 Overview: John Park, National Institutes of Health, Bethesda, MD

8:30-8:35 8 Zach Reitman, Duke University Medical Center, Raleigh, NC
Global and targeted approaches to analyze the glioma metabolome

8:40-8:45 9 Oscar A. Gonzales, Wake Forest University, Winston-Salem, NC
EphA2/eprhinA1: A potential role in invadopodia formation in GBM cells

8:50-8:55 10 Ji Young Yoo, Ohio State University, Columbus, OH
Anti-tumor efficacy of 34.5ENVE: A transcriptionally retargeted and “Vstat120” expressing oncolytic virus

9:00-9:05 11 Jan Gronych, German Cancer Research Center, Heidelberg, Germany
An activated BRAF induces pilocytic astrocytoma in mice


Session 4: New Gene and Immunotherapy
9:10-9:15 Overview: John Ohlfest, University of Minnesota, Minneapolis, MN

9:15-9:20 12 Xinggang Mao, Johns Hopkins University School of Medicine, Baltimore, MD
LIN28 promotes glioblastoma tumorgenicity through upregulation of HMGA2

9:25-9:30 13 Katherine Murphy, University of Minnesota, Minneapolis, MN
Enhanced anti-tumor immunity through OX40L signaling requires B cells

9:35-9:40 14 Veronique Frattini, IRCCS Foundation Neurological Institute, Milan, Italy
FOXP3, a candidate tumor suppressor for glioblastoma, inhibits proliferation and migration by inducing differentiation in glioma stem-like cells

9:45-10:00 Mingle together and more discussion

NOTE: Each talk is 5 minutes, followed by a 5 minute discussion

To RSVP for the meeting, click here.