Translational and clinical research on ependymomas
With generous philanthropic support, CERN (Collaborative Ependymoma Research Network) has been formed to focus research efforts on this rare tumor, and, through international collaborations, to acquire sufficient tumor material for analysis and accrue patients to clinical trials, to promote progress against adult and/or pediatric ependymoma. With coordinating centers at M. D. Anderson Cancer Center (under Mark Gilbert) and St. Jude Children’s Research Hospital (under Richard Gilbertson), CERN encompasses an additional 9 clinical centers in the US and Canada to maximize patient access, with the potential for adding more centers and accept patient referrals to extend this benefit. Projects range from stem cell biology and generation of ependymoma mouse models, to tumor tissue profiling, molecular drug target identification and targeted drug development, to a clinical trials network to quickly capitalize on findings. Additional information is available at http://www.cern-foundation.org.