The Hospital for Sick Children (1)
The Hospital for Sick Children
Pediatric Neuro-Oncology Program
555 University Ave.
Toronto, Ontario M5G 1X8
Canada
Research Categories:
-Novel drug therapies for pediatric brain tumors; clinical research, pilot studies, phase I/II/III studies
-Molecular biology of pediatric brain tumors
-Predicting risk of long term adverse effects in survivors of pediatric brain tumors
-Translational research in pediatric brain tumors
Research Interests/projects:
-Determination of the extent and role of monoallelic gene expression in low and high grade pediatric brain tumors
-Prediction of tumor resistance and normal brain sensitivity to cranial radiation in pediatric brain tumors
-Combined telomerase inhibition and drug screen as novel therapies for tumor initiating cells in pediatric nervous system
tumors
-Development of a mouse model for novel therapies in Choroid plexus carcinomas
-Genetics of pediatric brain stem glioma: from bench to bedside
-Predictors of functional and neuro-cognitive outcomes in long term surivors of pediatric low grade glioma
-Intervention studies (neuroprotective effects of exercise in children with brain tumors
-Clinical research: case reports, case series and case control studies, development and conduct of prospective clinical
trials including phase I to III studies, methodical approaches to clinical research and clinical epidemiology
-Twining/outrearch neuro-oncology programs using telemedicine
-Prediction of tumor resistance and normal brain sensitivity to cranial radiation in pediatric brain tumors
-Combined telomerase inhibition and drug screen as novel therapies for tumor initiating cells in pediatric nervous system
tumors
-Development of a mouse model for novel therapies in Choroid plexus carcinomas
-Genetics of pediatric brain stem glioma: from bench to bedside
-Predictors of functional and neuro-cognitive outcomes in long term surivors of pediatric low grade glioma
-Intervention studies (neuroprotective effects of exercise in children with brain tumors
-Clinical research: case reports, case series and case control studies, development and conduct of prospective clinical
trials including phase I to III studies, methodical approaches to clinical research and clinical epidemiology
-Twining/outrearch neuro-oncology programs using telemedicine
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