Tufts University

Tufts Medical Center
Tufts University School of Medicine
800 Washington St.
Neurology, Hematology and Oncology, Box 245
Boston, MA  02111
USA

 

Contact:
Jay-Jihuang Zhu, M.D., Ph.D.
jzhu@tuftsmedicalcenter.org
617-636-2694

 

    -Clinical research include clinical trials design and implementation, study of quality of life of patients receiving
     chemotherapy and radiation therapy, clinical comparative effectiveness and personalized medicine based on molecular

     profile, race, age and gender

    -Basic Science research include stem cell research of GBM tumors, tumor cell signal transduction, increase
     Temozolomide sensitivity through methylation of MGMT gene in transgenic model, microRNA in gliomas and
     nano-particle technology application in treatment of gliomas

 

Clinical: There are many opportunities of clinical trials design and implementation as well as participation. Here are a few examples at the time of submitting this form.
     -Design and implement a phase II clinical trial using combination of bevacizumab with temozolomide for treatment of
      high grade glioma
     -Design and implement a phase II clinical trial using Erbitux or other targeted therapy drugs with whole brain radiation for
      treatment of brain metastasis
     -Design and implement a phase II clinical trial using intravencular injection of Depocyt for treatment of glioma
     -Design and implement a phase II clinical trial studying quality of life patients with brain metastasis receiving

      chemotherapy and radiation therapy