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The Society for Neuro-Oncology hosted the 2020 Virtual Conference on Brain Metastases in association with the AANS/CNS Section on Tumors, on Friday, August 14, 2020, from 10 am – 3 pm CST

View the full conference

View the pre-recorded content and and electronic posters
Pre-Recorded Content  
Poster Presentations


Scientific Program Co-Chairs  Priscilla Brastianos, MD, Massachusetts General Hospital, Havard Medical School
Paul Kongkham, MD, PhD, Toronto Western Hospital, University Health Network
Rohan Ramakrishna, MD, Weill Cornell Medicine (AANS/CNS Section on Tumors Liaison)
David Shultz, MD, PhD, Princess Margaret Cancer Center

Invited speakers and top-scoring abstract presenters presented the latest in brain metastases treatment and research, with lively Q&A from the viewing audience. The first session focused on advances in systemic therapy, including clinical trial design and precision medicine approaches, and recent developments in radiation. The second session covered surgical advances and Leptomeningeal disease. The last session focused on basic science and translational talks. All accepted abstracts from this meeting are available in Neuro-Oncology Advances online supplement. Click here to view the supplement.  

Program Schedule

Session 1
systemic therapy, including clinical trial design and precision medicine approaches, and recent developments in radiation. 
Moderators: Rohan Ramakrishna, David Shultz 
FDA recommendations regarding efficacy endpoints and expanding eligibility criteria in clinical trials for patients with brain metastases  Amy Barone
Genetic Evolution of Brain Metastases: Implications for Precision Medicine  Priscilla Brastianos
Abstract #53: Tucatinib vs placebo added to trastuzumab and capecitabine for patients with previously treated HER2+ metastatic breast cancer (MBC) with brain metastases (BM) (HER2CLIMB)  Nancy Lin
NCIC CE7 - An Update on the Treatment of Multiple Brain Metastases  David Roberge
Abstract #25: Effect of stereotactic radiosurgery compared to whole-brain radiotherapy for limited brain metastasis on long term cognition and quality of life: A pooled analysis of NCCTG N107C/CEC.3 and N0574 (Alliance) randomized clinical trials  Joshua Palmer
Abstract #59: A radiomics-based machine learning model for distinguishing radiation necrosis from progression of brain metastases treated with stereotactic radiosurgery (SRS)  Xuguang Chen

 
Session 2
surgical advances and Leptomeningeal disease
Moderator: Adrienne Boire 
Surgery for Brain Metastases; Past, Present and Future Perspectives  Raymond Sawaya
Abstract #65: Invasive histopathology drives poor outcomes in surgically resected brain metastases  Matthew Danker
Abstract #11: Association of Tumor Exposure to Cerebrospinal Fluid Spaces to Leptomeningeal Disease in Patients with Brain Metastases  Kunal Patel
Abstract #57: Circulating tumor cells (CTC) in cerebrospinal fluid (CSF) as a predictor of survival in CNS metastases  Maria Diaz


Session 3
Moderator: Paul Kongkham 
Advances in Animal Models in Brain Metastases  Manuel Valiente
Abstract #29: Role of age and CNS myeloid cells on breast cancer brain metastasis  Alex Wu
Abstract #42: Identification of brain metastasis vulnerabilities using METPlatform  Lucia Zhu
Abstract #54: tGLI1 is an actionable therapeutic target in breast cancer brain metastases  Daniel Doheny